The Intein Database is a comprehensive on-line resource that includes the information's about the inteins. The Intein Database is a curated database devoted to inteins. Inteins are protein splicing elements that mediate a self-catalytic protein splicing reaction. The Intein Database presents general information's as well as detailed data for each intein, including tabu-lated comparisons and a advance search engine specific for keywords & sequences and several tools for the analysis of the inteins. the introduction page of The Intein Database provides an introduction to protein splicing and each section of the intein databse introduction link contains background materials for the general user.